Rotenone ≥97%, off-white powder

Supplier: MP Biomedicals
Danger

0215015410 0215015450 0215015401 0215015405
ICNA0215015410EA 881 SGD
ICNA0215015410 ICNA0215015450 ICNA0215015401 ICNA0215015405
Rotenone ≥97%, off-white powder
Rotenone

Rotenone is a naturally occurring botanical compound obtained from the roots of Derris sp.& Cube. It is an inhibitor of mitochondrial electron transport, specifically inhibiting NAD-linked substrate oxidation by mitochondria at the oxygen side of NADH dehydrogenase.
Rotenone is utilized as an insecticide. It can be used as neurotoxic agent that can produce a Parkinson-like condition as an animal model for study of etiology and interventions.
Inhibitor of mitochondrial electron transport at NADH: ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone is used to induce a Parkinson-like syndrome as an experimental model in rats.


  • Presentation: Off-White Powder
  • Extinction Coefficient (E1%): 19.2 (294 nm, ethanol)(Lit.)
  • Partition Coefficient: Octanol/Water Partition Coefficient-log Kow = 4.10 (Lit.)
  • Optical Rotation: -120° (1.38 g/100 mL chloroform at 25 °C) (Lit.)
  • Vapor Pressure: <1 x 10-5 mbar at 20 °C
  • Insoluble in water; Soluble in ethanol, methanol, acetone, carbon tetrachloride, chloroform, ether, or benzene.
  • Storage temperature: Room Temperature, protect from light, store under nitrogen

Formula: C₂₃H₂₂O₆
Boiling Pt: 210…220 °C (0,5 mmHg)) (lit.)
Melting Pt: 159…164 °C (lit.)
Density: 1,27 (20 °C) (lit.)
Storage Temperature: Ambient
MDL Number: MFCD09025614
CAS Number: 83-79-4
UN: 2811
ADR: 6.1,III

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Specification Test Results

Identity Test Passes
Purity ≥97%
FTIR Conforms to Standard

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