EGS [Ethylene glycolbis(succinic acid-N-hydroxysuccinimide ester)], powder
Supplier: MP Biomedicals
Synonyms:
Bis(2,5-dioxopyrrolidin-1-yl) O,O'-ethane-1,2-diyl disuccinate, EGS, Ethylene glycol disuccinate di(N-succinimidyl) ester, Ethylene glycol bis(succinimidyl succinate), Di(N-succinimidyl) ethylene glycol disuccinate
Soluble in acetic acid: water (1:1): ≤50 mg/ml, DMF.
Ethylene Glycol bis(Succinic Acid N-Hydroxysuccinimide Ester) is a homobifunctional, cleavable cross-linking reagent. It is typically, coupled to molecules containing primary amines by amide bonds buffered at pH 7,5 (6,5 - 8,5). The linkage provides a 12-atom spacer.
Ethylene Glycol bis(Succinic Acid N-Hydroxysuccinimide Ester) can be used to produce succinic acid 2-[3-(doxorubicin-3'-N-yl)-3-oxopropionyloxy]-ethyl ester N-hydroxysuccinimidyl ester with adriamycin at temperature of 20 °C.
Formula:
C₁₈H₂₀N₂O₁₂ MW: 456,36 g/mol |
MDL Number:
MFCD00049057 CAS Number: 70539-42-3 |
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