Trimethylsulphonium hydroxide 0.2 M in methanol alkylation reagent, for GC derivatisation

Supplier: MACHEREY-NAGEL
Danger

Synonyms: TMSH

701520.201 701520.101 701520.110 701520.510
MANA701520.201EA 719 SGD
MANA701520.201 MANA701520.101 MANA701520.110 MANA701520.510
Trimethylsulphonium hydroxide 0.2 M in methanol alkylation reagent, for GC derivatisation
Trimethylsulphonium Hydroxide

Methylation with TMSH is recommended for free acids, chlorophenoxycarboxylic acids, their salts and derivatives as well as for phenols and chlorophenols. Lipids or triglycerides can be converted to the corresponding fatty acid methyl esters (FAMEs) by a simple transesterification.


  • Methylation derivatives are generally stable
  • Wide range of reaction conditions (strongly acidic - strongly basic)
  • Some reactions can be achieved with water present
  • A removal of excess TMSH reagent is not required, due to a pyrolysis in the GC injector at 250 °C


Concentration: 0.2 M in methanol

Formula: C₃H₁₀OS
MW: 94,17 g/mol
MDL Number: MFCD00216756
CAS Number: 17287-03-5
UN: 1992
ADR: 3,II

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