Spermine-(N,N'-bis(3-aminopropyl)-1,4-butanediamine) ≥97%, colorless solid
Supplier: MP Biomedicals
|
Danger
|
Synonyms:
N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine), Spermine
Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.
Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.
Caution: Research Use Only (RUO). Desiccate, store under nitrogen.
Formula:
C₁₀H₂₆N₄ MW: 202,35 g/mol Boiling Pt: 141…142 °C (0,5 mmHg) Melting Pt: 28…30 °C (lit.) Storage Temperature: Refrigerator |
MDL Number:
MFCD00008215 CAS Number: 71-44-3 |
Specification Test Results
Identity Test | Passes |
Purity | ≥97% |
FTIR | Conforms to Standard |
pH (0.5% aq soln) | 11 - 14 |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...