Bovine haemoglobin
Supplier: MP Biomedicals
Hemoglobin is the major component of red blood cells, and is responsible for their red color. A major oxygen-transporting component of red blood cells.
- Standardised for protease assay
Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorises a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.
Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide. Hemoglobin is a tetramer composed of 2 pairs of polypeptide chains called globins, and 4 heme groups. Each polypeptide chain is bound to one heme. Iron is coordinated to 4 pyrrole nitrogens of protoporphyrin IX and to an imidazole nitrogen of a histidine residue from the globin side of the porphyrin.
Hemoglobin is used to study paradigm for the regulation of gene expression and cellular differentiation.
Hemoglobin is soluble in water (1 part in 7 of water), and slowly soluble in glycerol.
Caution: Research Use Only (RUO).
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