EDTA (ethylenediamine tetraacetic acid) ≥99.5%, white powder for electrophoresis
Supplier: MP Biomedicals
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Warning
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Synonyms:
Kestranal® A, OmniPur® EDTA, Edetic acid, Ethylenediaminetetraacetic acid, Ethylenedinitrilotetra-acetic acid, 2,2',2'',2'''-(Ethane-1,2-diylbis(azanetriyl))tetraacetic acid, (Ethylenedinitrilo)tetraacetic acid, Idranal® II
Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals.
- Auto Ignition: > 200 °C (DIN 51794) (Lit.)
- pKa: 2.0, 2.7, 6.2, 10.3 (Lit.)
For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.
EDTA is an inhibitor of metalloproteases and metal-activated proteases at an effective concentration of 1-10 µM.
Soluble in 3M NaOH (160 mg/mL); 1 M aq soln: Clear, Colorless & Complete, No Black Specks, Haze Free.
Caution: Research Use Only (RUO).
Formula:
C₁₀H₁₆N₂O₈ MW: 292,25 g/mol Melting Pt: 236…246 °C (lit.) Density: ∼860 kg/m³ (bulk density) Storage Temperature: Ambient |
MDL Number:
MFCD00003541 CAS Number: 60-00-4 |
Specification Test Results
Identity Test | Passes |
Purity | ≥99.5% |
FTIR | Conforms to Standard |
pH (sat'd soln) | 2-3 |
Heavy Metals (as Pb) | ≤10ppm |
Iron (Fe) | ≤50ppm |
Sulfated Ash | ≤0.1% |
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