Propyl-3,4,5-trihydroxybenzoate, off-white powder
Supplier: MP Biomedicals
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Warning
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Synonyms:
Gallic acid propyl ester, Propyl gallate, Propyl 3,4,5-trihydroxybenzoate, Progalline P, N-Propyl gallate
n-Propyl gallate is an ester formed by the condensation of gallic acid and propanol. This antioxidant has been added to foods containing oils and fats to prevent oxidation.
n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0,25 µM when it was combined with copper concentrations at 5 µM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0,5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
Soluble in ethanol (50 mg/ml).
Caution: Research Use Only (RUO).
Formula:
C₁₀H₁₂O₅ MW: 212,2 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00002196 CAS Number: 121-79-9 |
Specification Test Results
Identity Test | Passes |
FTIR | Conforms to Standard |
Melting Point | 140 - 150 °C |
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