Poly-D-lysine hydrobromide (synthetic), white powder
Supplier: MP Biomedicals
Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein.
It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
This product is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. After absorption to the culture surface, poly-D-lysine increases the number of positively charged cell binding sites.
Caution: Research Use Only (RUO).
Formula:
C₆H₁₅BrN₂O₂ MW: 227,102 g/mol Storage Temperature: Freezer |
CAS Number:
27964-99-4 |
Specification Test Results
Identity Test | Passes |
Average Molecular Weight | 4,000-15,000 |
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