Poly-D-lysine hydrobromide (synthetic), white powder

Supplier: MP Biomedicals

0210269450 0210269480 0210269490 0210269491 0210269410
ICNA0210269450EA 292 SGD
ICNA0210269450 ICNA0210269480 ICNA0210269490 ICNA0210269491 ICNA0210269410
Poly-D-lysine hydrobromide (synthetic), white powder
Poly-D-lysine hydrobromide

Poly-lysine is a polycation which binds to DNA, red cell membrane and any negatively charged protein.


It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.


This product is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. After absorption to the culture surface, poly-D-lysine increases the number of positively charged cell binding sites.


Caution: Research Use Only (RUO).

Formula: C₆H₁₅BrN₂O₂
MW: 227,102 g/mol
Storage Temperature: Freezer
CAS Number: 27964-99-4

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Specification Test Results

Identity Test Passes
Average Molecular Weight 4,000-15,000

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