Aztreonam, white powder
Supplier: MP Biomedicals
Synonyms:
2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulpho-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropionic Acid, 2-((((Z)-1-(2-Aminothiazol-4-yl)-2-(((2S,3S)-2-methyl-4-oxo-1-sulphoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoic acid
Aztreonam is the first totally synthetic monocyclic β-lactam antibiotic that displays a high degree of resistance to β-lactamase degradation. It has high specificity for gram-negative aerobic rods.
Aztreonam specifically targets the penicillin binding protein 3 (PBP-3) of Gram-negative bacteria. It is also effective against such Enterobacteriaceae as E. coli, Klebsiella, Proteus, Providencia, Salmonella, Serratia, Shigella, and Yersinia species.
Soluble in DMF and DMSO; slightly soluble in ethanol and methanol; practically insoluble in toluene, chloroform and ethyl acetate.
Caution: Research Use Only (RUO).
Formula:
C₁₃H₁₇N₅O₈S₂ MW: 435,43 g/mol Melting Pt: 227 °C (dec., lit.) Storage Temperature: Refrigerator |
MDL Number:
MFCD00072145 CAS Number: 78110-38-0 |
Specification Test Results
Identity Test | Passes |
Potency (as is) | Report Result (µg/mg) |
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