Sodium-2-propylvalerate, crystalline powder

Supplier: MP Biomedicals
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Synonyms: Sodium Valproate, 2-Propylvaleric Acid Sodium Salt, 2-Propylpentanoic Acid Sodium Salt, Sodium 2-Propylpentanoate, Valproic Acid Sodium Salt

0215206410 0215206425 0215206480
ICNA0215206410EA 179 SGD
ICNA0215206410 ICNA0215206425 ICNA0215206480
Sodium-2-propylvalerate, crystalline powder
Sodium-2-propylvalerate

Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3α and GSK-3β. Valproic Acid has been reported to be a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400 μM for HDAC1), thereby relieving HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells.


In animal studies, Valproic Acid has been observed to reduce tumor growth and metastasis formation. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A in the inhibition of histone deacetylase. This compound is also an inhibitor of the CYP2C9 enzyme.


Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder.


Soluble in water (50 mg/ml) clear, colorless solution.


Caution: Research Use Only (RUO).

Formula: C₈H₁₅O₂Na
MW: 166,20 g/mol
Storage Temperature: Ambient
MDL Number: MFCD00078604
CAS Number: 1069-66-5

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