Sodium-2-propylvalerate, crystalline powder
Supplier: MP Biomedicals
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Warning
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Synonyms:
Sodium Valproate, 2-Propylvaleric Acid Sodium Salt, 2-Propylpentanoic Acid Sodium Salt, Sodium 2-Propylpentanoate, Valproic Acid Sodium Salt
Sodium Valproate is reported to cause inositol depletion, activate the ERK pathway, inhibit GSK-3α and GSK-3β. Valproic Acid has been reported to be a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400 μM for HDAC1), thereby relieving HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells.
In animal studies, Valproic Acid has been observed to reduce tumor growth and metastasis formation. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A in the inhibition of histone deacetylase. This compound is also an inhibitor of the CYP2C9 enzyme.
Anti-convulsant that also has efficacy as a mood stabilizer in bipolar disorder.
Soluble in water (50 mg/ml) clear, colorless solution.
Caution: Research Use Only (RUO).
Formula:
C₈H₁₅O₂Na MW: 166,20 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00078604 CAS Number: 1069-66-5 |
Specification Test Results
Identity Test | Passes |
FTIR | Conforms to Reference |
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