1,1-Dimethylbiguanide hydrochloride, white powder
Supplier: MP Biomedicals
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Warning
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Synonyms:
AMPK Signaling Activator VII, Metformin, Metformin hydrochloride, 1,1-Dimethylbiguanide Hydrochloride
1,1-Dimethylbiguanide hydrochloride (Metformin) is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
1,1-Dimethylbiguanide Hydrochloride has various medical uses such as in polycystic ovary syndrome, non-alcoholic fatty liver disease and diabetes mellitus type 2. It may also reduce weight gain in people taking atypical antipsychotics.
Soluble in water (100 mg/ml - clear, colorless solution), 95% ethanol; insoluble in ether, acetone or chloroform.
Formula:
C₄H₁₂ClN₅ MW: 165,625 g/mol Melting Pt: 214…224 °C Storage Temperature: Ambient |
MDL Number:
MFCD00012582 CAS Number: 1115-70-4 |
Specification Test Results
Identity Test | Passes |
FTIR | Conforms to Standard |
Melting Point | 214 - 224 °C |
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