DNA sodium salt (Deoxyribonucleic acid sodium salt) (from fish sperm), off-white powder
Supplier: MP Biomedicals
Synonyms:
Thymonucleic acid sodium salt, DNA sodium salt
Deoxyribonucleic acid is a polynucleotide . It is an essential component of chromosomes in cell nuclei. It is the carrier of genetic material. It contains information in chemical code to direct the development of the cell according to its inheritance. The purine and pyrimidine bases of the nucleosides are primarily adenine, guanine, cytosine and thymine. The sugar is D-2-deoxyribose.
The nucleosides are linked together by phosphates in diester linkage from the 3'-hydroxyl of one sugar to the 5'-hydroxyl of the next. The repeating sugar-phosphate linkage forms the backbone of the single polynucleotide strand which is the primary structure of DNA. Chemical analysis of DNA from different species show that the purine content is equal to the pyrimidine content; adenine content equal to thymine; guanine equal to cytosine. DNA also acts as a template in the formation of ribonucleic acids, which play a fundamental role in the synthesis of proteins in the cell.
Deoxyribonucleic acid sodium salt has been used in a study to evaluate the cytotoxicity of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin. Deoxyribonucleic acid sodium salt has also been used in a study to develop a simple method for extracting DNA from Cryptosporidium oocysts.
Most DNA is soluble in water or aqueous buffers. Slight heating may help. The addition of SDS or similar detergent may help solubilise DNA; however, detergents tend to denature the DNA into shorter strands.
Highly polymerised (DNA which has not undergone any additional processing after isolation).
Storage Temperature:
Refrigerator |
MDL Number:
MFCD00130922 CAS Number: 9007-49-2 |
Specification Test Results
Identity Test | Passes |
Source | Fish Sperm |
Moisture | Report Result |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...