β-Cyclodextrine, white powder
Supplier: MP Biomedicals
Synonyms:
Caraway, Cycloheptaamylose, β-Cyclodextrin, Cyclomaltoheptaose, Schardinger β-Dextrin, Betadex
β-cyclodextrin is most commonly used as a complexing agent. It is reported to be useful for the selective precipitation of enantiomeric, positional or structural isomers. It also forms a water soluble complex with dansyl chloride for fluorescent labeling of proteins.
Cyclodextrins are cyclic oligosaccharides consisting of 6, 7, or 8 glucopyranose units with hydrophobic interiors, usually referred to as α-, β-, or γ-cyclodextrins, respectively. Lipophilic drugs of a size compatible with the hydrophobic core of a cyclodextrin can form complexes, resulting in increased aqueous solubility of the drugs. Cyclodextrins are non-toxic in many species (mice and rabbits), and do not denature proteins or interfere with enzymatic reactions.
Soluble in water, 1 M NH4OH: 50 mg/ml (clear, colorless solution).
Formula:
C₄₂H₇₀O₃₅ MW: 1134,98 g/mol Melting Pt: 298…300 °C (lit.) Density: 1,624 g/cm³ (lit.) Storage Temperature: Ambient |
MDL Number:
MFCD00078139 CAS Number: 7585-39-9 |
Specification Test Results
Identity Test | Passes |
FTIR | Conforms to Standard |
pH (1% aq soln) | 5 - 7.5 |
Loss on Drying | ≤14% |
Optical Rotation | 158 ± 6° (c=1,water) |
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