Trichloroacetic acid (TCA), powder

Supplier: MP Biomedicals

Synonyms: TCA

0219052180 0219052190 0219052191
ICNA0219052180EA 91.3 SGD
ICNA0219052180 ICNA0219052190 ICNA0219052191
Trichloroacetic acid (TCA), powder
Trichloroacetic acid (TCA)

Trichloroacetic acid is used in protein precipitation; has been used to determine protein concentration by quantitative precipitation.


  • Poison/deleterious substance code: 2 to 58
  • Chloride= ≤0,002%


It is also Used as a decalcifier and fixative in microscopy. A protocol for the precipitation of nucleic acids can be found in molecular cloning. Rats exposed to chronic sublethal amounts of trichloroacetic acid displayed an increase in serum bilirubin with a decrease in hematological proteins and cholesterols along with significant decreases in red blood corpuscles, mean cell volume, mean corpuscular hemoglobin, hemoglobin and hematocrit. In mice the production of liver tumors was associated to Trichloroacetic acid, which is also a known mouse hepatocarinogen. On the guinea pig trichloroacetic acid was observed to be a mild alergen on the skin.


Poison/deleterious substance code: 2 to 58
Chloride= ≤0,002%


Soluble in water(10% aq soln) - clear, colorless solution; very soluble in ethanol or ether. Decomposed by heating with caustic alkalies into chloroform and alkali carbonate. Long term storage of aqueous solutions of less than 30% strength is not recommended. Decomposition products are chloroform, hydrochloric acid, carbon dioxide and carbon monoxide.

Formula: Cl₃CCOOH
MW: 163,39 g/mol
MDL Number: MFCD00004177
CAS Number: 76-03-9
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