Chlorhexidine gluconate 20% in aqueous solution
Supplier: MP Biomedicals
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Danger
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Synonyms:
1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide] digluconate, Peridex, 1,1'-Hexamethylenebis[5-(p-chlorophenyl)biguanide] (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid(1:2), Chlorhexidine digluconate
Chlorhexidine digluconate, a bis(biguanide) family cationic broad spectrum antibiotic is an antiseptic and disinfectant agent. It is effective against a wide range of bacteria, some fungi and some viruses, and an agent for the prevention of gingivitis. Chlorhexidine digluconate solution inhibits oxygen utilization which leads to a reduction in bacterial ATP . Commercial ophthalmic products have used this agent to replace thimerosal as a preservative; however, it can cause skin irritation.
Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs. It has been used to study how essential oils improve skin antisepsis when combined with chlorhexidine digluconate and is used for skin permeation studies. Chronic rinsing with chlorhexidine has been shown to decrease the saltiness of NaCl and the bitterness of quinine. Used in conjuction with cetyltrimethylammonium bromide (CTAB) can increase its effectiveness.
Cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilisation of the outer bacterial membrane. It is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
Dilute solutions of chlorhexidine (<1,0% w/v) may be sterilised by autoclaving at 115 °C for 30 minutes or at 121 to 123 °C for 15 minutes.
Formula:
C₂₂H₃₀Cl₂N₁₀·2C₆H₁₂O₇ MW: 897,76 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00083599 CAS Number: 18472-51-0 UN: 3082 ADR: 9,III |
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