AEBSF hydrochloride (4-(2-aminoethyl)benzenesulphonylfluoride hydrochloride) ≥97%, white powder
Supplier: MP Biomedicals
Synonyms:
4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride, AEBSF hydrochloride
AEBSF hydrochloride is a covalent binding serine protease inhibitor, belongs to the family of irreversible sulphonyl fluoride inhibitors that block trypsin and chymotrypsin-type enzymes.
Similar in structure to the commonly used inhibitor PMSF, AEBSF offers better solubility in water, lower toxicity, greater stability and higher inhibitory activity.
Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0,25 mM.
Soluble in methanol(10 mg/ml-clear, colorless solution)
Synonyms include AEBSF; 4-(2-Aminoethyl)-Benzenesulphonyl Fluoride Hydrochloride; p-Aminoethylbenzenenesulphonyl fluoride.
Formula:
C₈H₁₁ClFNO₂S MW: 239,69 g/mol |
MDL Number:
MFCD00132962 CAS Number: 30827-99-7 UN: 3261 ADR: 8,II |
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