AEBSF hydrochloride (4-(2-aminoethyl)benzenesulphonylfluoride hydrochloride) ≥97%, white powder

Supplier: MP Biomedicals

Synonyms: 4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride, AEBSF hydrochloride

0219350310 0219350350 0219350380 0219350390 0219350391
ICNA0219350310EA 87.1 SGD
ICNA0219350310 ICNA0219350350 ICNA0219350380 ICNA0219350390 ICNA0219350391
AEBSF hydrochloride (4-(2-aminoethyl)benzenesulphonylfluoride hydrochloride) ≥97%, white powder
AEBSF hydrochloride (4-(2-Aminoethyl)benzenesulphonylfluoride hydrochloride)

AEBSF hydrochloride is a covalent binding serine protease inhibitor, belongs to the family of irreversible sulphonyl fluoride inhibitors that block trypsin and chymotrypsin-type enzymes.


Similar in structure to the commonly used inhibitor PMSF, AEBSF offers better solubility in water, lower toxicity, greater stability and higher inhibitory activity.


Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0,25 mM.


Soluble in methanol(10 mg/ml-clear, colorless solution)


Synonyms include AEBSF; 4-(2-Aminoethyl)-Benzenesulphonyl Fluoride Hydrochloride; p-Aminoethylbenzenenesulphonyl fluoride.

Formula: C₈H₁₁ClFNO₂S
MW: 239,69 g/mol
MDL Number: MFCD00132962
CAS Number: 30827-99-7
UN: 3261
ADR: 8,II

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