Ristocetin A ≥90%, off-white powder

Supplier: MP Biomedicals

0219548905 0219548925
ICNA0219548905EA 172 SGD
ICNA0219548905 ICNA0219548925
Ristocetin A ≥90%, off-white powder
Ristocetin A

Ristocetin A is an antibiotic that belongs to the class III glycopeptides. The compound has activity against gram-positive and gram-negative bacteria, and can be used in chromatography. Ristocetin A is structurally related to the glycopeptide antibiotics Teicoplanin and vancomycin.


Ristocetin A has platelet aggregating activity and has been used in platelet aggregation studies. Studies have demonstrated that Ristocentin A dimerizes and creates two binding sites for cell wall peptides.


Ristocetin activates platelets. Ristocetin-induced platelet agglutination (RIPA) is decreased in patients undergoing chronic hemodialysis. Together with increased plasma glycocalicin levels (a product of enzymatic cleavage of GPIb), RIPA may contribute to diminished platelet adhesion to vascular subendothelium and increased bleeding associated with uremia. Addition of ristocetin and vWf caused specific agglutination of rGPIbα-liposomes suporting the potential use of rGPIbα-liposomes to enhance platelet function in vivo and support hemostasis in thrombocytopenic individuals.


Soluble in 1 N HCl (50 mg/ml - clear and colorless to pale yellow); soluble in water (clear 5 mg+ 0,25 ml, amber solution).

Formula: C₉₅H₁₁₀N₈O₄₄
MW: 2067,937 g/mol
Storage Temperature: Refrigerator
CAS Number: 1404-55-3

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Specification Test Results

Identity Test Passes
Potency (µg/mg) Report Result
Purity ≥90% Ristocetin A
Ristocetin B Sulfate Report Result

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