Bovine aprotinin (from Lung), MP Biomedicals

Supplier: MP Biomedicals

0219038210 0219038250
ICNA0219038210EA 1680 SGD
ICNA0219038210 ICNA0219038250
Bovine aprotinin (from Lung), MP Biomedicals
Proteins and Peptides

Aprotinin is a protein consisting of 58 amino acids, arranged in a single polypeptide chain that is cross-linked by three disulphide bridges. It is found in bovine lymph nodes, lung, parotid gland, spleen, liver, pancreas, seminal vesicles, thyroid gland, kidney, mucous membranes of the trachea and esophagus, ovaries, heart, posterior pituitary and cartilage.


  • Extinction coefficient (E1%)(280 nm)=8,3 (water)
  • Isoelectric point (pI): 10,5
  • Soluble in water and in aqueous buffers of low ionic strengths


It is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. It forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or <3.


Unit definition: One KIU (Kallikrein Inactivating Unit) is identical to the quantity of protease inhibitor that has the ability to inhibit 2 Kallikrein units by 50% under optimal conditions.

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