Guanosine 97.0-103.0%, off-white powder

Supplier: MP Biomedicals
Danger

Synonyms: 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one

0210190705 0210190725 0210190780 0210190790
ICNA0210190705EA 116 SGD
ICNA0210190705 ICNA0210190725 ICNA0210190780 ICNA0210190790
Guanosine 97.0-103.0%, off-white powder
Guanosine

Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of adeoxyribose ring it is known as deoxyguanosine.
Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein. The antiviral drug aciclovir, often used in herpes treatment, is structurally similar to guanosine.


  • Presentation: Off white powder
  • Clear to very slightly hazy colorless to faint yellow solution at 50mg/ml in Formic acid : water (1:1)
  • Storage temperature: Room Temperature

Formula: C₁₀H₁₃N₅O₅
MW: 283,24 g/mol
Melting Pt: 250 °C (lit.)
Storage Temperature: Ambient
MDL Number: MFCD00010182
CAS Number: 118-00-3

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Specification Test Results

Identity Test Passes
Purity 97-103%
FTIR Conforms to Standard
UV/Vis: l max (water) 251 ± 3 nm
OD250/OD260 1.3
OD280/OD260 0.69
OD290/OD260 0.26

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