5-Chloro-2'-deoxyuridine, white powder
Supplier: MP Biomedicals
|
Warning
|
Synonyms:
5-Chloro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
5-Chloro-2'-deoxyuridine (CldU) is a thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine.
5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).
- Presentation: White Powder
- Soluble in 1M NH4OH (20 mg/1 mL-colorless solution).
- Storage temperature: -20 °C
Storage temperature: -20 °C
Formula:
C₉H₁₁ClN₂O₅ MW: 262,65 g/mol Melting Pt: 166…176 °C Storage Temperature: Freezer |
MDL Number:
MFCD00006531 CAS Number: 50-90-8 |
Specification Test Results
Identity Test | Passes |
FTIR | Conforms to Standard |
Melting Point | 166-176°C |
UV/Vis: l max (water) | 276 ± 3nm |
Learn more
About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...