Sulphamethazine sodium salt, white powder
Supplier: MP Biomedicals
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Warning
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Synonyms:
4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulphonamide sodium salt, Sodium ((4-aminophenyl)sulphonyl)(4,6-dimethylpyrimidin-2-yl)amide, Sulphadimidine sodium salt, Sodium sulphamethazine
Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.
Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.
- Presentation: White Powder
- H2O: soluble (50 mg/mL)
- Storage temperature: Store at +4 °C.
Storage temperature.: +4 °C
Formula:
C₁₂H₁₃N₄NaO₂S MW: 300,31 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00068333 CAS Number: 1981-58-4 |
Specification Test Results
Identity Test | Passes |
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