Dextran sulphate sodium salt, M.W. ∼36000 - 50000, white powder, Colitis Grade

Supplier: MP Biomedicals

Synonyms: Dextran sulphate sodium from Dextran

0216011050 0216011090 0216011010 0216011001 0216011025 0216011080
ICNA0216011050EA 2030 SGD
ICNA0216011050 ICNA0216011090 ICNA0216011010 ICNA0216011001 ICNA0216011025 ICNA0216011080
Dextran sulphate sodium salt, M.W. ∼36000 - 50000, white powder, Colitis Grade
Dextran sulphate sodium salt

Dextran sulphate is a polyanionic derivative of dextran produced by esterification of Dextran with chlorosulphonic acid. Dextran sulphate sodium (DSS) is the sodium salt which is a white to off-white powder freely soluble in water and salt solutions to form a stable, clear solution. The sulphur content is approximately 17% which corresponds to an average of 1.9 sulphate groups per glucosyl residue of the dextran molecule.


Dextran Sulfate Sodium (DSS) which has proven to have versatile value in Biomedical/clinical research. DSS can be used to study Colitis (Inflammatory Bowel disease) as well as an antiviral as agent.


Inflammatory Bowel Disease (IBD) is characterized by chronic and relapsing inflammation of the gastrointestinal tract which is associated with increased risk of developing colitis-associated cancer. Several animal models have been used to study colitis and one such model involves the oral administration of dextran sodium sulfate (DSS) in the drinking water of mice leading to chronic colitis. This DSS induced colitis model is spontaneous and is used to assess the therapeutic potential of treatments for IBD.

Formula: (C₆H₇Na₃O₁₄S₃)n
Storage Temperature: Ambient
MDL Number: MFCD00081551
CAS Number: 9011-18-1

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Specification Test Results

Identity Test Passes
Moisture <10%
Residue on Ignition <50%
Sulphur ~18 - 20%
Glucose 35 - 50%
pH (1% aq soln) 5 - 7,5
Specific Rotation +75° to +105°
Free Sulphate ≤0,2%

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