Gentamicin sulphate

Supplier: MP Biomedicals
Danger

Synonyms: NMD Inhibitor II, Garamycin, Gentamicin sulphate salt, Gentiomycin C

02190057.2 0219005705 0219005710 0219005701 0219005725
ICNA02190057.2EA 112 SGD
ICNA02190057.2 ICNA0219005705 ICNA0219005710 ICNA0219005701 ICNA0219005725
Gentamicin sulphate
Gentamicin sulphate

Gentamicin sulpahte is used as a selection agent (gentamicin-resistance gene) in molecular biology applications.It is used to treat many types of bacterial infections, particularly those caused by gram-negative organisms.


It causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilises the membrane, and forms holes in the cell surface. Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria.


H2O: soluble 50 mg/ml (As a stock solution. Stock solutions should be stored at −20 °C.) (Lit.)

Melting Pt: 218…237 °C
Storage Temperature: Ambient
MDL Number: MFCD00270181
CAS Number: 1405-41-0
EINECS: 215-778-9
Merck Index: 13,04403

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Specification Test Results

Synonyms Garamycin; Gentamicin sulphate salt; Gentiomycin C
Form White powder
Storage Store at +4 °C
Loss on Drying ≤18,0 %
Optical Rotation 107° to +121° (10 mg/ml, water)
pH 3,5 - 5,5 (1 in 25, in water)
Potency ≥590 µg/mg

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