TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride) ≥99%, Reagent Grade

Supplier: MP Biomedicals

Synonyms: Tris(hydroxymethyl)methylamine hydrochloride, 2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride, Trizma® hydrochloride, Trizma(R) hydrochloride, Tris(hydroxymethyl)aminomethane hydrochloride, TRIS HCl, Tromethane hydrochloride, Tris-HCl, Tris(hydroxymethyl)methylammonium chloride, Trometamol hydrochloride, THAM HCl

02103130.2 02103130.1 02103130.5 0210313001 0210313005
ICNA02103130.2EA 203 SGD
ICNA02103130.2 ICNA02103130.1 ICNA02103130.5 ICNA0210313001 ICNA0210313005
TRIS HCl (tris(hydroxymethyl)aminomethane hydrochloride) ≥99%, Reagent Grade
TRIS HCl (Tris-(hydroxymethyl) aminomethane hydrochloride)

Tris and Tris Hydrochloride have been useful as buffers in a wide variety of biological systems. Uses include pH control in vitro and in vivo for body fluids and in buffering systems for electrophoresis applications.


Tris has been used as a starting material for polymers, oxazolones (with carboxylic acids) and oxazolidines (with aldehydes). It can be used for the direct standardization of a strong acid solution; the equivalence point can be determined either potentiometrically or by use of a suitable indicator such as 3-(4-Dimethylamino-1-naphthylazo)-4-methoxybenzenesulfonic acid .


The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0,03 unit per °C decrease in temperature, and decreases 0,03-0,05 unit per ten-fold dilution.

Formula: NH₂C(CH₂OH)₃·HCl
MW: 157,6 g/mol
Melting Pt: 150…152 °C
Storage Temperature: Ambient
MDL Number: MFCD00012590
CAS Number: 1185-53-1
EINECS: 214-684-5
Merck Index: 12,09902
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