N,N-Dimethylformamide dimethyl acetal methylation reagent, for GC derivatisation

Supplier: MACHEREY-NAGEL
Danger

Synonyms: 1,1-Dimethoxytrimethylamine, Esterate M, N,N-Dimethylformamide Dimethyl Acetal, 1,1-Dimethoxy-N,N-dimethylmethylamine, DMF-DMA

701430.110 701430.201
MANA701430.110EA 162 SGD
MANA701430.110 MANA701430.201
N,N-Dimethylformamide dimethyl acetal methylation reagent, for GC derivatisation
N,N-Dimethylformamide dimethyl acetal

Methylation with DMF-DMA can be applied for fatty acids, primary amines and partially amino acids forming N-dimethyl-aminomethylene amino acid methyl esters. DMF-DMA is a poor solvent, for this reason it is necessary to use a mixture of DMF-DMA with pyridine, THF, acetone (barbiturates) or another solvent.


  • Methylation derivatives are generally stable
  • Wide range of reaction conditions (strongly acidic - strongly basic)
  • Some reactions can be achieved with water present

Formula: C₅H₁₃NO₂
MW: 119,16 g/mol
Boiling Pt: 106–107 °C (760 mm Hg)
Density: 0,897 g/cm³ (d20°/4°)
MDL Number: MFCD00008482
CAS Number: 4637-24-5
UN: 3316
ADR: 9,II

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