MOPS-Na, white powder
Supplier: MP Biomedicals
Synonyms:
3-(N-Morpholino)propanesulphonic acid sodium salt, Sodium 3-morpholinopropane-1-sulphonate, Sodium 4-morpholin-1-ylpropylsulphonate, MOPS sodium salt
MOPS is used as a biological buffer.
Soluble in water (to approximately 33% w/w - clear, colourless solution).
MOPS is a zwitterionic amino acid which acts as one of the "Good" buffers. It is a structural analog to MES; however, MOPS is a more suitable biological buffer than MES because the pH range is closer to pH 7,4. A buffer using MOPS free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH (pKa ±1), using about a half-equivalent of NaOH.
A buffer using MOPS sodium salt can be made by mixing equimolar MOPS free acid and MOPS sodium salt solutions to attain a buffer of the desired pH. Titration of a solution of MOPS sodium salt with HCl results in a solution that will contain NaCl, so the ionic strength will be higher than appropriate for some applications. Concentrations higher than 20 mM should not be used with mammalian cell cultures.
Formula:
C₇H₁₄NNaO₄S MW: 231,25 g/mol Storage Temperature: Ambient |
MDL Number:
MFCD00064350 CAS Number: 71119-22-7 EINECS: 428-420-3 |
Specification Test Results
pH | 9,0 - 10,5 (1% aq solution) |
pka | pKa −7,2 at 25 °C |
Water Content | ≤0,5% |
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