Penicillin G potassium salt
Supplier: MP Biomedicals
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Warning
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Synonyms:
6-(2-Phenylacetamido)penicillanic acid potassium salt, Potassium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, Penicillin G potassium, Potassium [2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, Benzylpenicillin potassium salt
Penicillin G is a narrow spectrum antibiotic.
Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs) which inhibits peptidoglycan chain cross-lining. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.
It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G potassium salt is used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking..
Soluble in water (100 mg/ml) clear,colourless to light yellow.
Formula:
C₁₆H₁₇KN₂O₄S MW: 372,49 g/mol Melting Pt: 214…217 °C Density: 1,359 g/cm³ (20 °C) Storage Temperature: Refrigerator |
MDL Number:
MFCD00036193 CAS Number: 113-98-4 EINECS: 204-038-0 Merck Index: 12,07225 |
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