L-Arginine hydrochloride 98.5-101.0% USP, Multi-Compendial, meets analytical specification of ChP, BP, JP, Ph. Eur., Macron Fine Chemicals™

Supplier: Avantor Performance Materials

Synonyms: H-L-Arg-OH.HCl, (S)-2-Amino-5-guanidinopentanoic acid hydrochloride, (S)-(+)-Arginine HCl, H-Arg-OH·HCl, L-Arginine, hydrochloride, (S)-(+)-Arginine hydrochloride, H-Arg-OH.HCl, L-Arg, L(+)-Arginine monohydrochloride, L(+)-Arginine hydrochloride

MACR4922-09EA 4380 SGD
MACR4922-09 MACR4922-06 MACR4922-07
L-Arginine hydrochloride 98.5-101.0% USP, Multi-Compendial, meets analytical specification of ChP, BP, JP, Ph. Eur., Macron Fine Chemicals™
L-Arginine hydrochloride
Formula: C₆H₁₅ClN₄O₂
MW: 210,66 g/mol
Melting Pt: 218 °C
Density: 1,42 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00064550
CAS Number: 1119-34-2

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Specification Test Results

GMP Manufactured Product
Meets B.P. Chemical Specifications
Meets ChP Chemical Specifications
Meets J.P. Chemical Specifications
Meets U.S.P Requirements
Meets E.P. Chemical Specifications
Preserve in Tight Containers
CAUTION: For Manufacturing, processing or repackaging
Bulk Pharmaceutical Chemical
USP - Assay (C6H14N402·HCl) (dried basis) 98.5 - 101.5%
USP - Identification Passes Test
USP - Specific Rotation (A]2°AO (+) 21.4 - 23.6°
USP - Loss on Orying at 105 °C ≤0.2%
USP - Residue on Ignition ≤0.1%
USP - Sulfate (S04) ≤0.03%
USP - Related Compounds - Individual Impurities ≤0.5%
USP - Related Compounds - Total Impurities ≤2.0%
USP - Chloride (Cl) 16.5 - 17.1%
EP/BP - Assay (C6H14N402·HCl) (dried basis) 98.5 - 101.0%
EP/BP - Identification A Passes Test
EP/BP - Identification B Passes Test
EP/BP - Identification E Passes Test
EP/BP - Appearance of Solution Passes Test
EP/BP - Specific Rotation (A]2°AO (+) 21.0 - 23.5°
EP/BP-Ninhydrin-Positive Substances-Each ≤0.2%
EP/BP-Ninhydrin-Positive Substances-Total Impurities ≤0.5%
EP/BP - Sulfate (S04) ≤300 ppm
EP/BP - Ammonium (NH4) ≤0.02%
EP/BP - Iron (Fe) ≤10 ppm
EP/BP - Loss on Orying ≤0.5%
EP/BP - Ash (sulfated) ≤0.1%
JP - Assay (C6H14N402·HCl) (dried basis) 98.5 - 101.0%
JP - Identification Passes Test
JP - 0ptical Rotation (+) 21.5 - 23.5°
JP - pH (1 in 10) 4.7 - 6.2
JP - Clarity and Color of Solution Passes Test
JP - Sulfate (S04) ≤0.028%
JP - Ammonium (NH4) ≤0.02%
JP - Arsenic (As) ≤2 ppm
JP - Related Substances Passes Test
JP - Loss on Orying at 105 °C ≤0.20%
JP - Residue after Ignition ≤0.10%
Endotoxin Concentration, IU/mg, For Information only
ChP - Transmittance of solution ≥ 98.0%
ChP - Sulfates ≤0.02%
ChP - Ammonium ≤0.02%
ChP - Loss on drying @ 105 °C ≤0.2%
ChP - Residue on ignition ≤0.1%
ChP - Heavy metals ≤0.001%
ChP - Arsenic ≤0.0001%
ChP - Identification 1 (TLC) Passes Test
ChP - Identification 2 (IR) Passes Test
ChP - Chloride Content 16.5 - 17.1%
ChP - 0ther amino acids (TLC)(<=0.2%, one spot only) Passes Test
ChP - Proteins Passes Test
ChP - Iron ≤0.001%
ChP - Specific Rotation @ 20 °C (+) 21.5 - 23.5
ChP - Phosphates ≤0.02%
ChP - Assay (dried basis) 98.5 - 101.0%

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