(3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulphonate) ≥98%, white powder

Supplier: MP Biomedicals
Warning

Synonyms: (3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxypropanesulphonate), CHAPSO

0219032025 02190320.5 0219032001 0219032005
ICNA0219032025EA 4540 SGD
ICNA0219032025 ICNA02190320.5 ICNA0219032001 ICNA0219032005
(3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulphonate) ≥98%, white powder
(3-((3-Cholamidopropyl)dimethylammonio)-2-hydroxy-1-propanesulphonate)

CHAPSO is the hydroxy analog of CHAPS; a non denaturing zwitterionic detergent for solubilising proteins, especially integral membrane proteins while maintaining the functional capability of the protein of interest.


  • Useful for the solubilisation of integral membrane proteins
  • Critical micelle concentration (CMC): 8 mM
  • Aggregation Number:11


It has a more polar head group than CHAPS, giving it a greater solubility. CHAPSO has a high CMC (8 mM) and does not denature membrane-bound proteins. It can solubilise the opiate receptor in a state exhibiting reversible binding of opiates.


CHAPSO is the hydroxy analog of CHAPS; a nondenaturing zwitterionic detergent for solubilising proteins, especially integral membrane proteins while maintaining the functional capability of the protein of interest. It has a more polar head group than CHAPS, giving it a greater solubility. CHAPSO has a high CMC (8 mM) and does not denature membrane-bound proteins. It can solubilise the opiate receptor in a state exhibiting reversible binding of opiates.


Soluble in water (100 mg/ml - clear, colourless to slight yellowish solution), methanol (40 mg/ml- clear, colourless solution).

Formula: C₃₂H₅₈N₂O₈S
MW: 630,89 g/mol
Melting Pt: 184…186 °C (lit.)
Storage Temperature: Ambient
CAS Number: 82473-24-3

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Specification Test Results

Identity Test Passes
Purity ≥98%
FTIR Conforms to Standard
pH (10% aq soln) 5,0 - 9,0
OD350 nm (1% aq soln) <0,04

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