Iodoacetamide 98% stabilised

Supplier: Thermo Scientific
Danger

Synonyms: 2-Iodoacetamide

Stabilization: Moistened with water ∼5-8%

A14715.06 A14715.14 A14715.22
ALFAA14715.06EA 61.8 SGD
ALFAA14715.06 ALFAA14715.14 ALFAA14715.22
Iodoacetamide 98% stabilised
Iodoacetamide

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation.


2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.


Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation

Formula: ICH₂CONH₂
MW: 184,96 g/mol
Boiling Pt: 266 °C (1013 hPa)
Melting Pt: 92…95 °C (dried)
Storage Temperature: Refrigerator
MDL Number: MFCD00008028
CAS Number: 144-48-9
EINECS: 205-630-1
UN: 2811
ADR: 6.1,III

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