5-Bromo-2'-deoxyuridine (broxuridine) ≥99%, white powder

Supplier: MP Biomedicals
Danger

Synonyms: 5-Bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, 5-Bromo-2'-deoxyuridine, 5-BrdU

0210017101 02100171.2 02100171.5 0210017105
ICNA0210017101EA 252 SGD
ICNA0210017101 ICNA02100171.2 ICNA02100171.5 ICNA0210017105
5-Bromo-2'-deoxyuridine (broxuridine) ≥99%, white powder
5-Bromo-2'-deoxyuridine (Broxuridine)

5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. It can be used to label DNA which can be used in conjunction with BrdU Monoclonal Antibody for the immunohistochemical analysis of cell proliferation.


5-Bromo-2'-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.


Biochem/physiol Actions: Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase.


Soluble in water (10 mg/ml or 50-100 mg/ml with heat) or sodium hydroxide (50 mg/ml).

Formula: C₉H₁₁BrN₂O₅
MW: 307,10 g/mol
Melting Pt: 183…193 °C
Storage Temperature: Freezer
MDL Number: MFCD00006529
CAS Number: 59-14-3
EINECS: 200-415-9

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Specification Test Results

Identity Test Passes
Purity ≥99%
FTIR Conforms to Standard
UV/VIS: l max (water) 279 ± 2, 209 ± 3 nm

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