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5'-O-(4,4'-Dimethoxytrityl)thymidine ≥98%

Supplier: Thermo Scientific

Description: 5'-O-(4,4'-Dimethoxytrityl)thymidine ≥98%

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N-Isobutyryl-5'-O-[(diisopropylamino)(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 97%

Catalog Number: (ALFAH52411.03)

Supplier: Thermo Scientific

Supplier Article Number:: H52411.03

Description: N-Isobutyryl-5'-O-[(diisopropylamino)(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine 97%

UOM: 1 * 1 g

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N-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine ≥97%

Supplier: Thermo Scientific

Description: N-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine ≥97%

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4,4'-Dimethoxytrityl chloride ≥98%

Supplier: Thermo Scientific

Description: 4,4'-Dimethoxytrityl chloride ≥98%

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Thymidine (2'-deoxythymidine) ≥99%

Supplier: Thermo Scientific

Description: Thymidine (2'-deoxythymidine) ≥99%

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Thymidine-5'-monophosphate disodium salt

Supplier: Thermo Scientific

Description: Thymidine-5'-monophosphate disodium salt

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VWR®, Cod Uracil-DNA glycosylase

Supplier: VWR Chemicals

Description: Uracil-DNA glycosylase (UNG), cod is a thermolabile recombinant enzyme produced in <i>E. coli</i> (ung-) using a modified ung gene derived from Atlantic cod. It degrades uracil-containing single- and double-stranded DNA, but not RNA or thymidine-containing DNA, by hydrolysing the N-glycosidic bond between deoxyribose sugar and the base in uracil. This generates alkaline-sensitive apyramidinic sites in the DNA that will be cleaved upon a combination of alkaline conditions and high temperature.

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Thymidine (2'-deoxythymidine) 100X (1.6 mM)

Catalog Number: (PANBP04-56020)

Supplier: PAN BIOTECH

Supplier Article Number:: P04-56020

Description: Thymidine (2'-deoxythymidine) 100X (1.6 mM)

UOM: 1 * 20 mL

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5-Bromo-2'-deoxyuridine (broxuridine) ≥99%, white powder

Supplier: MP Biomedicals

Description: 5-Bromo-2’-deoxyuridine is a thymidine analog and useful for the study of DNA synthesis where it is incorporated into DNA in place of thymidine. It can be used to label DNA which can be used in conjunction with BrdU Monoclonal Antibody for the immunohistochemical analysis of cell proliferation.

5-Chloro-2'-deoxyuridine, white powder

Supplier: MP Biomedicals

Description: 5-Chloro-2'-deoxyuridine (CldU) is a thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine.
5-Chloro-2′-deoxyuridine (CldU) is used as a thymidine analogue to study the miscoding potential of hypochlorous acid damage to DNA and DNA precursors. When used with antibody based immunofluorescent imaging, 5-Chloro-2′-deoxyuridine incorporation may be used in protocols to identify sites of DNA replication. CldU may be used as a labeling substrate in conjunction with other halogenated uridine labeling substrates such as bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU).

Trimethoprim, white powder

Supplier: MP Biomedicals

Description: Trimethoprim is an antibacterial agent; a specific inhibitor of formylation; a dihydrofolate reductase inhibitor.
Trimethoprim is primarily used as an antibacterial agent. It has dihydrofolate reductase inhibitor activity with selectivity for the prokaryote enzyme. It is used to treat urinary tract infections, mild acute prostatitis, recurrent cystitis, asymptomatic bacteriuria during pregnancy and respiratory tract infections.
The combination of trimethoprim and sulfamethoxazole interferes with the cellular metabolism of folic acid in the bacterial cell by blocking the biosynthesis of nucleotides. Trimethoprim binds to dihydrofolate reductase and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis.